IL4-10 fusion protein: a novel immunoregulatory drug combining activities of interleukin 4 and interleukin 10
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چکیده
منابع مشابه
Immunoregulatory role of interleukin 10 in rheumatoid arthritis
The presence and the role of interleukin 10 (IL-10), a potent cytokine synthesis inhibitory factor and antiinflammatory cytokine, were investigated in rheumatoid arthritis (RA). The expression of both mRNA and protein for IL-10 could be demonstrated in RA and osteoarthritis (OA) joints. Human IL-10 mRNA could be demonstrated by polymerase chain reaction amplification of cDNA made by reverse tra...
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مقدمه: پرفشارخونی یکی از بیماریهای همراه با بیماری دیابت نوع 2 است که در بیشتر بیماران دیابتی نوع 2 دیده می‌شود. هدف از انجام این تحقیق بررسی اثر ورزش ایروبیک بر روی فشارخون زنان دیابتی نوع 2 است. روش پژوهش: تعداد 32 بیمار دیابتی نوع 2 که دارای فشارخون بالا بودند به صورت تصادفی به دو گروه تقسیم شدند: گروه ورزش ایروبیک (16 نفر) و گروه کنترل (بدون ورزش) (16 نفر)...
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BACKGROUND IL4/IL4RA pathway plays an important role in atopy and asthma. Different polymorphisms in IL4 and IL4RA genes have been described. Particularly, -33C>TIL4 and 576Q>RIL4RA SNPs have been independently associated to atopy and asthma. The purpose of this study was to analyse these polymorphisms in a population of patients with a well-characterized asthma phenotype. METHODS A total of ...
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ABSTRACT Introduction: Peptic ulcer is a common problem in medicine with serious impacts on the quality of life of patients. It has been shown that Helicobacter pylori infection is related with inflammatory responses of gastric mucosa. However, some patients remain asymptomatic. Sustained colonization and chronic inflammation increase the risk of gastritis and peptic ulcer. The a...
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ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 2018
ISSN: 0009-9104
DOI: 10.1111/cei.13224